The 24th Annual College of Veterinary Medicine and Biomedical Sciences Research Day was held on January 28, 2023.

Research Day is a showcase of cutting-edge research projects and approaches from members of the College of Veterinary Medicine and Biomedical Sciences community. The annual symposium is an opportunity for students, faculty, and staff to present their work and talents, connect with other graduate students and faculty at CSU, and learn about other disciplines.

Dr. Dan Regan, the head of the Investigational Pathology Laboratory at the Flint Animal Cancer Center, was presented with the 2022 Zoetis Veterinary Research Excellence Award. He gave the keynote speech titled – “Everything I know I Learned from Dogs.”

Many other members of the Flint Animal Cancer Center participated with oral and poster presentations. Participants include:

  • Thomas Lee of the Boss Lab – Local immune response to radiation therapy and combined myeloid cell targeted therapy in a dog model of sinonasal carcinoma
  • Marika Klosowski of the Regan Lab – Breast cancer cell co-culture with primary lung fibroblasts is associated with modulation of cytokine secretion and extrinsic stromal-mediated drug resistance
  • Thomas Burnett of the Avery Lab – Quantitative assessment of genes involved in early lymphopoiesis using droplet digital
    PCR (ddPCR) to distinguish immature lymphoid neoplasms in the dog
  • Jenna Cao of the Dow Lab – Canine osteosarcoma as a translational model for advancing solid tumor CAR T cell therapy
  • Kristen Farrell of the Thamm Lab – Omacetaxine reduces c-MYC expression and demonstrates antitumor effects in osteosarcoma
  • Molly Gasparini – Retrospective investigation of the correlation between clinical cause of death and necropsy cause of death due to malignant neoplasia in a tertiary academic hospital population
  • Laurel Haines of the Regan Lab – Osteosarcoma exosome priming of alveolar macrophages promotes formation of a pre-metastatic niche |
  • Cullen Hart of the Boss Lab – Local immune responses to radiation therapy and myeloid cell-targeted therapy in naturally occurring canine sinonasal carcinoma
  • Elise Martens – A Retrospective Review of Chemotherapy-Related Extravasation Events in Dogs and Cats
  • Alysa Nelson of the Dow Lab – Triple Drug Immunotherapy for Treatment of Metastatic Osteosarcoma: Understanding Immune Mechanisms of Action
  • Ashley Parker – Retrospective evaluation of large granular lymphocyte (LGL) lymphoma in dogs
  • Mary Jo Thometz of the Avery Lab – Epidemiology of canine B cell leukemia and lymphoma

We’re incredibly proud of our team for their diverse and exciting research achievements. The annual Research Day is a celebration of their hard work and dedication to furthering our understanding of cancer in both companion animals and humans.

Dr. Regan receiving the Zoetis Award
Elise Martens with her poster on chemotherapy-related extravasation events
Thomas Burnett presenting to Dr. Dow
Laurel Haines presenting her Osteocarcoma poster
Dr. Parker with her poster on LGL Lymphomas in dogs
Kristen Farrell with her Osteosarcoma poster
Thomas Burnett with his droplet digital PCR (ddPCR) poster
Dr. Gasparini with her poster on malignant neoplasia
Cullen Hart presenting his radiation therapy and myeloid cell-targeted therapy poster
Dr. Boss and Dr. Lee following his oral presentation on local immune response to radiation therapy and combined myeloid cell targeted therapy in a dog model of sinonasal carcinoma