F18 FDG PET/CT Following Radiation Therapy

Trial closed August 2022.

Patient Disease:

Canine Osteosarcoma

Study Name:

F18 FDG PET/CT Following Radiation Therapy

Purpose of the study:

  • To determine if PET/CT can be used to assess if dogs treated with stereotactic radiation therapy (SRT) still have cancer remaining after treatment

Primary Eligibility Criteria:

  • Dogs with osteosarcoma that will be treated with SRT
  • No prior chemotherapy for tumor
  • No radiation treatment in the last 3 months to any area of the body
  • Otherwise healthy and free of other major diseases
  • Pets must come to CSU for all visits related to the clinical trial

Study Protocol:

  • PET/CTs are performed prior to starting SRT and 3-4 months after completion of radiation
  • Aspirates of affected lymph nodes and any other tissues suspected to have evidence of cancer based on imaging are performed immediately after each PET/CT
  • Dogs are treated with SRT (not considered to be part of the clinical trial)
  • Someone will contact you once monthly between the two PET/CT scans and then every 2-3 months after the second PET/CT for an update on your pet

Owner Responsibilities:

  • Costs of diagnostics to determine eligibility for clinical trials
  • All costs related to SRT including treatment of side effects due to radiation
  • Make and keep all appointments according to the treatment protocol

Financial Incentives:

  • All costs related to the PET/CT scans including imaging and anesthesia costs are covered by the study, as well as the costs related to the aspirates that are performed after imaging
  • The study will also cover the costs of blood work that needs to be done prior to the 2nd PET/CT
  • The cost of treatment of any side effects that occur as a results of study procedures will be covered by the study


If you have further questions about any of our clinical trials, please submit an online consult form. Your consult will then be directed to our trials team. Requests are typically returned within 5 business days

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