Canine Brain Tumor Vaccine Clinical Trial

Patient Disease:

Canine Glioma

Study Name:

Canine Brain Tumor Vaccine Clinical Trial

Purpose of the study:

  • Evaluation of preliminary tumor response to vaccine that targets cancer stem cells as well as vaccine tolerability

Primary Eligibility Criteria:

  • Dogs with glioma type tumors based on MRI characteristics
  • Patients must still be in overall good health and stable condition
  • Not dependent on prednisone to control clinical signs
  • Seizures (if occurring) must be controlled with anti-convulsant medication
  • Measureable disease present and visible on MRI
  • Pets must come to CSU for all visits related to the clinical trial

Study Protocol:

  • Pre-enrollment screening: physical/neurological exam, blood tests, MRI of the brain
  • Needle biopsy to confirm glioma diagnosis
  • Treatment of tumor with stereotactic radiotherapy (SRT)
  • Vaccination, physical exam, study blood sampling every other week for 6 treatments then monthly boosters
  • Follow up MRI scans at 6th vaccine treatment and then every 3 months

Owner Responsibilities:

  • You are responsible for initial screening tests (consultation/physical exam, blood and urine tests, MRI of brain)
  • You are expected to make and keep all appointments associated with the study

Financial Incentives:

  • Study covers all costs related to the trial
  • Up to $500 is available for treatment of vaccine-related adverse events

If you have further questions about any of our clinical trials, please submit an online consult form. Your consult will then be directed to our trials team. Requests are typically returned within 5 business days.

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