PET/CT and cytology for canine lymphoma

Patient Disease:

Canine Lymphoma

Study Name:

F18 FDG PET/CT and cytology for canine lymphoma

Purpose of the study:

  • To determine if PET/CT can be used to assess if dogs with lymphoma still have cancer remaining while undergoing treatment with the CHOP chemotherapy protocol

Primary Eligibility Criteria:

  • Dogs with newly diagnosed B-cell lymphoma that will be treated with CHOP chemotherapy protocol
  • No prior chemotherapy including prednisone for lymphoma
  • No radiation treatment in the last 3 months to any area of the body
  • Otherwise healthy and free of other major diseases
  • Pets must come to CSU for all visits related to the clinical trial

Study Protocol:

  • PET/CTs are performed prior to starting chemotherapy, halfway through the CHOP chemotherapy protocol, and 1-3 weeks after completion of chemotherapy
  • Aspirates of affected lymph nodes and any other tissues suspected to have evidence of lymphoma based on imaging are performed immediately after each PET/CT
  • Blood samples for study purposes are collected prior to each PET/CT
  • Dogs are treated with the standard 15-week CHOP chemotherapy protocol (not considered to be part of the clinical trial)

Owner Responsibilities:

  • Costs of diagnostics to determine eligibility for clinical trial
  • All costs related to CHOP chemotherapy protocol including treatment of side effects related to chemotherapy
  • Make and keep all appointments according to the treatment protocol

Financial Incentives:

  • All costs related to the PET/CT scans including imaging and anesthesia costs are covered by the study, as well as the costs related to the aspirates that are performed after imaging
  • The study will also cover the costs of blood work that needs to be done prior to the 2nd and 3rd PET/CTs
  • A $1000 credit will be applied to the patient’s account at the VTH to be put towards the costs of chemotherapy
  • The cost of treatment of any side effects that occur as a result of study procedures will be covered by the study

If you have further questions about any of our clinical trials, please submit an online consult form. Your consult will then be directed to our trials team. Requests are typically returned within 5 business days.

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