Safety and Biologic Effects of Intranodal Injection of a Nonspecific Immunomodulator in Canine B Cell Lymphoma

Patient Disease:

Canine B Cell Lymphoma

Study Name:

Purpose of the study:

To measure the safety and immune effects of injecting a novel non-specific immunomodulatory drug into a lymph node in dogs with B cell lymphoma

Primary Eligibility Criteria:

Confirmed diagnosis of B cell lymphoma
Must have at least one external lymph node that is at least 20 mm in diameter
Two-week washout from chemotherapy, one week for steroids, 6 weeks for radiation therapy
Must have adequate blood work and be feeling well
Pets must come to CSU for all visits related to the clinical trial

Study Protocol:

At the first visit, dogs will have a physical exam and lymph node measurements. Samples from one lymph node will be taken with a needle for study purposes and then the study drug will be injected into the lymph node. Vitals will be monitored for 6 hours after treatment.
Dogs will return the following day (24 hours after injection) for a physical exam, lymph node measurements, and needle aspirates of the lymph node for study purposes.
The study is complete after this visit

Owner Responsibilities:

Costs of tests to diagnose lymphoma and determine eligibility for clinical trial
Make and keep all appointments according to the treatment protocol

Financial Incentives:

Study covers all costs related to trial including overnight hospitalization if elected by owner + $500 credit to account at the VTH

If you have further questions about any of our clinical trials, please submit an online consult form. Your consult will then be directed to our trials team. Requests are typically returned within 5 business days.