Patient Disease:

Canine Mast Cell Tumor

Study Name:

Cryotherapy for Canine Mast Cell Tumors

Purpose of the study:

  • To evaluate the mast cell tumor (MCT) tissue changes associated with a new cryotherapy probe. This information will be used to determine if this less expensive carbon dioxide-based probe can be used to treat other dogs having MCTs that are not geographically near veterinary specialty centers, to improve the accessibility of veterinary care.

Primary Eligibility Criteria:

  • Confirmed diagnosis of MCT with a single tumor that is amenable to wide surgical excision
    • Tumors must be 2-5 cm in one axis and 1-3 cm in the other axis
  • Adequate organ function to safely undergo anesthesia
  • 72-hour washout from corticosteroids; no other prior treatment for MCT allowed
  • No systemic signs related to MCT
  • Pets must come to CSU for all visits related to the clinical trial

Study Protocol:

  • Once enrolled, dogs will be anesthetized and will receive cryotherapy to the mast cell tumor; they will be hospitalized overnight to monitor for any side effects of the procedure
  • Dogs will return 14 to 21 days later for wide surgical excision of the MCT
  • Study is complete after surgery day

Owner Responsibilities:

  • Costs of diagnostics to diagnose the mast cell tumor and any diagnostics recommended by your oncology clinician
  • Make and keep all appointments as required by the clinical trial protocol

Financial Incentives:

  • Once enrolled, the study will cover the costs related to both study visits including anesthesia, cryotherapy, overnight hospitalization, and costs of surgery to remove the tumor with analysis by histopathology
  • Up to $1000 is available to cover costs of treatment of side effects related to study procedures

If you have further questions about any of our clinical trials, please submit an online consult form. Your consult will then be directed to our trials team. Requests are typically returned within 5 business days.