Validation of intraoperative Raman spectroscopy

Patient Disease:

Brain Tumor

Study Name:

  • Validation of intraoperative Raman spectroscopy to detect cancerous cells during brain tumor resection

Purpose of the study:

  • To determine if Raman spectroscopy can correctly identify canine brain tumor cells and canine normal brain cells at the tumor site, as well as in excised tissue.
  • To improve safety and accuracy of brain tumor resection, and reduce side effects of surgery

Primary Eligibility Criteria:

  • Dogs with a brain tumor diagnosis, deemed surgically resectable based on MRI characteristics
  • No prior radiation or chemotherapy
  • Must be essentially normal systemically (physical exam and lab work)

Study Protocol:

  • Pre-enrollment: Physical exam, lab testing (CBC, chemistry panel, UA), brain MRI
  • Once eligibility confirmed, the dog will undergo brain surgery with use of the Raman spectroscopy. Recordings at each site will be compared with histopathology results

Owner Responsibilities:

  • The owner is responsible for all other costs relating to the dog's care that are not covered by the study.

Financial Incentives:

  • The study will apply a credit of $5000 to your VTH account to be put towards the costs associated with brain surgery. The credit will be applied following surgery as long as the dog has been deemed eligible to participate.

If you have further questions about any of our clinical trials, please submit an online consulting form. Your consult will then be directed to an appropriate oncology clinician. Requests are typically returned within 5 business days.