Flint Animal Cancer Center

Study to Compare Different Imaging Methods for Diagnosis and Staging of Canine Insulinoma

Patient Disease:

Canine Insulinoma

Study Name:

Study to Compare Different Imaging Methods for Diagnosis and Staging of Canine Insulinoma

Purpose of the study:

  • To compare the ability of multiple imaging procedures to detect insulinoma tumors in dogs, and to determine how well these imaging procedures can identify the tumor and if any of these procedures has an advantage over the other

Primary Eligibility Criteria:

  • Dogs with a suspected diagnosis of insulinoma based on clinical signs and blood work changes (persistently low glucose; insulin: glucose ratio)

  • No concurrent diseases that would be incompatible with prolonged or repeated anesthesias

Study Protocol:

  • Day 1: Dogs anesthetized for CT/angiogram of chest and abdomen and whole-body PET/CT scan

  • Day 2: Anesthesia for MRI of abdomen +/- surgery to obtain samples for tumor for diagnosis

    • Surgery may be done on a separate day, but all study procedures must occur within a one-week period

Owner Responsibilities:

  • You are responsible for the initial testing to determine study eligibility (bloodwork and chest x-rays) and any other tests recommended by your pet’s oncologist

  • You are expected to make and keep all appointments associated with the study

Financial Incentives:

  • All costs related to the study protocol including the costs of imaging including anesthesia and the biopsy sample analysis at the time of surgery

  • Hospitalization between imaging studies or if required to watch your pet in the rare instance they have trouble with the anesthesia will also be covered