Name of Investigator: Susan L. Kraft
Title: Associate Professor
Contact Information:
Email Address: susan.kraft@colostate.edu
Work Address (mailing): CSU Animal Cancer Center, Veterinary Teaching Hospital, 1678 Campus Delivery, 300 West Drake Road, Fort Collins, CO 80523
Office Location (Building/Room #): ACC 154
Office Phone Number: (970) 297-0350
Laboratory Location (Building/Room #): ACC 155, 158
Laboratory Phone Number: (970) 297-1293
Biography of Investigator:
Dr. Kraft’s research and
special clinical imaging interests are cancer imaging particularly with
magnetic resonance imaging (MRI) and computed tomography (CT). In
addition to board certification in veterinary diagnostic imaging, she
is also boarded in veterinary radiation oncology with an interest in
the application of imaging modalities for treatment planning as well as
evaluation of radiation effects.
Ph.D., Washington State University, 1991
DVM, Washington State University, 1985
B.S., Biology, University of Alaska, 1981
Classes Taught/Currently Teaching:
Guest lecturer for: VM619 Neuroimaging, VM581 Cancer Biology, ERHS721 Radiation Oncology, VS 660 Neurosurgery
Research Focus:
Dr. Kraft's research interests are in
cancer imaging particularly with Magnetic Resonance Imaging/
spectroscopy and computed tomography, and also including imaging-guided
radiation therapy as well as neuroradiology. Dr. Kraft's research
involves the use of MRI as a means of physiological assessment of
cancer for better characterization and to evaluate its response to
therapy. This particularly involves imaging of parameters important to
treatment response such as tumor vascularity, hypoxia, diffusion,
perfusion, and tumor metabolism.
Future Direction:
Dr.
Kraft serves as director of the Magnetic Resonance Imaging service at
the CSU Animal Cancer Center, and will also direct the PET-CT research
program as CSU’s new PET-CT instrument as installed in 2009.
Name of Laboratory:
Robert and Eva Knight MRI Suite
Laboratory Personnel:
Billie Arceneaux
List of Major Laboratory Equipment:
General Electric Signa 9.1 LX MRI instrument with MR multinuclear spectroscopy capabilities
Current Work/Projects:
Refereed Publications:
Ehrhart N, Kraft SL, Conover D,
Rosier R, Schwarz E, 2008, Quantification of massive allograft healing
with dynamic contrast enhanced-MRI and cone beam CT. Clin Orthop Relat Res. 466, 1897-1904.
Kraft SL,
Randall E, Wilhelm M, Lana S, 2007, Development of a whole body MR
imaging protocol in normal dogs and canine cancer patients. Vet Radiol Ultrasound. 48, 212-220.
Kraft SL,
Ehrhart EJ, Gall D, Klopp L, Gavin P, Tucker R, Bagley R, Kippenes H,
DeHaan C, Pedroia V, Partington B, Olby N, 2007, Magnetic Resonance
Imaging Characteristics of 18 Peripheral Nerve Sheath Tumors of the
Canine Brachial Plexus. Vet Radiol Ultrasound. 48, 1-7.
Meola S, Swiderski J, Kraft SL, Palmer RH, 2007, What’s your diagnosis? – spinal cord perforation with IVD extrusion. JAVMA. 230, 1629-1630.
Brennan G, Podell M, Wack R, Kraft SL, Bielefeldt Ohmann H, VandeWoude S, 2006, Neurologic disease in Panthera leo with low titer lion lentivirus infection. J Clin Microbiology. 44, 4345-4552.
Huang Z, Haider MA, Kraft SL,
Chen Q, Blanc D, Wilson B, Hetzel F, 2006, Response of prostate gland
to Pd-Bacteriopheophorbide (Tookad) photodynamic therapy monitored with
magnetic resonance imaging. Lasers in Surgery and Medicine. 38, 672-681.
Garcia GE, Wisniewski H, Lucia S, Arevalo N, Kraft SL,
Strange R, Kumar AP, 2006, 2-Methoxyestradiol inhibits prostate tumor
development in transgenic adenocarcinoma of mouse prostate: Role of
tumor necrosis factor-alpha-stimulated gene 6. Clinical Cancer Research. 12, 980-988.
Heng HG, Wrigley RH, Kraft SL, Powers BE, 2005, Fat is responsible for an intramural radiolucent band in the feline stomach wall. Vet Rad and Ultrasound. 46, 54-57.
Kraft SL,
Dailey D, Kovach M, Stasiak K, Bennett J, McFarland, CT, McMurray DN,
Izzo AA, Orme IM, Basaraba RJ, 2004, MRI of pulmonary lesions in guinea
pigs infected with Mycobacterium tuberculosis. Infection and Immunity. 72, 5963-5971.
Kraft SL, 2004, Images from the 2003 Certification Examination of the ACVR: Special Procedures and Alternate Imaging Section. Vet Radiol Ultrasound. 45, 1-3.
Fish PH, Carpenter JW, Kraft SL, 2004, Diagnosis and treatment of a cerebral ischemic attack in a chimpanzee (Pan troglodytes). J Zoo Wildlife Med. 35, 203-207.
Young B, Klopp L, Albrecht M, Kraft SL, 2004, MRI diagnosis of a cervical foreign body. Vet Radiol Ultrasound. 45, 538-541.
Lora-Michiels M, Biller DS, Olsen D, Hoskinson JJ, Kraft SL, Jones JC, 2003, The accessory lung lobe in thoracic disease: A case series and anatomical review. J Am Anim Hosp Assoc. 39, 452-458.
Marolf A, Kraft SL, Lowry J, Pelsue D, Vier J, 2002, Radiographic diagnosis: Incidental right kidney herniation. Vet Radiol Ultrasound. 43, 237-40.
Kippenes H, Gavin P, Kraft SL, Sande R, Tucker R, 2001, Mensuration of the normal pituitary gland from magnetic resonance images in 96 dogs. Vet Radiol Ultrasound. 42, 130-133.
Detweiler DA, Carpenter JW, Kraft SL, Andrews GA, Hoskinson JJ, 2000, Radiographic diagnosis: Avian Cloacal Adenocarcinoma. Vet Radiol Ultrasound. 41, 539-542.
Smith SA, Lewis DC, Kraft SL, Freeman C, 2000, Plasma pharmacokinetics of warfarin enantiomers in cats. J Vet Pharmacol Ther. 23, 329 - 337.
Tucker DW, Olsen D, Kraft SL, Andrews GA, Gray AP, 2000, Primary hemangiosarcoma of the iliopsoas muscle eliciting a peripheral neuropathy. J Am Anim Hosp Assoc. 36, 163-167.
Smith SA, Lewis DC, Kraft SL, Coyle J, Freeman LC, 2000, Pharmacodynamics of warfarin in cats. J Vet Pharmacol Ther. 23, 339 - 344.
Grimsley-Cook A, Gaughan E, Kraft SL, 2000, Atypical sequestration and cortical healing after radial trauma in a yearling filly. Equine Pract. 22, 6-9.
Harkin K, Goggin JM, DeBey BM, Kraft SL, deLaHunta A, 1999, MRI of hereditary polioencephalomyelopathy in an Australian cattle dog. J Am Vet Med Assoc. 214, 1342-1344.
Smith SA, Goggin JM, Kraft SL, 1999, Asymptomatic pleuroperitoneal diaphragmatic hernia in a cat (What is your diagnosis?). J Am Vet Med Assoc. 214, 479-80.
Basaraba RJ, Kraft SL, Andrews GA, Leipold HW, Small D, 1998, An ovarian teratoma in a cat. Vet Pathol. 35, 141-144.
Perchellet EM, Ladesich JB, Chen Y, Sin HS, Dua DM, Kraft SL,
Perchellet JP, 1998, Antitumor activity of tricyclic pyrone analogs, a
new synthetic class of microtubule de-stabilizing agents, in the murine
EMT6 mammary tumor cell line in vitro. Anticancer Drugs. 9, 565-576.
Kraft SL, Mussman J, Smith T, Biller DS, 1998, Magnetic resonance imaging of lumbosacral discospondylitis. Vet Radiol Ultrasound. 39, 9-13.
Smith SA, Biller DS, Hoskinson JJ, Kraft SL, 1998, Diagnostic imaging in the diagnosis of biliary obstruction. Compend Cont Educ. 20, 1225-1234, 1260.
Newell SW, Perchellet EM, Ladesich JB, Freeman JA, Chen Y, Sin HS, Hua DH, Kraft SL,
Basaraba RJ, Perchellet JP, 1998, Tricyclic pyrone analogs: A new class
of microtubule-disrupting anticancer drugs effective against murine
leukemia cells in vitro. Int J Oncol. 12, 433-442.
Perchellet JP, Newell SW, Ladesich JB, Perchellet EM, Chen Y, Hua DH, Kraft SL, Basaraba RJ, 1997, Antitumor activity of novel tricyclic pyrone analogs in murine leukemia cells in vitro. Anticancer Res. 17, 2427-2434.
Gavin PR, Kraft SL, Huiskamp R, Coderre JA, 1997, A review: CNS effects and normal tissue tolerance in dogs. J Neurooncol. 33, 71-80.
Kraft SL,
Hoskinson JJ, Mussman J, Michaels W, McLaughlin R, Gaughan E, Roush J,
1998, Development of interactive computer-based case-oriented learning
programs in veterinary orthopedic radiology. Vet Radiol Ultrasound. 39, 98-105.
Kraft SL,
Gavin PR, DeHaan CE, Moore M, Wendling LR, Leathers CW, 1997,
Retrospective evaluation of magnetic resonance imaging characteristics
of 50 intracranial tumors. J Vet Intern Med. 11, 218-225.
Armbrust L, Kraft SL, Cowan L, Hoskinson J, 1997, Imaging diagnosis: Ureteral calculi in a cat. Vet Radiol Ultrasound. 38, 360-362.
Kraft SL, Hoskinson JJ, 1997, Computer-based case oriented learning: Teaching effectiveness in veterinary orthopedic radiology. J Vet Med Educ. 24, 25-30.
Kraft SL,
Gavin PR, Leathers CW, DeHaan CE, Bauer WF, Dorn RV, Griebenow ML,
1994, Biodistribution of boron in dogs with spontaneous intracranial
tumors following borocaptate sodium administration. Cancer Res. 54, 1259-1263.
DeHaan CE, Kraft SL, Gavin PR, Wendling LR, Griebenow ML, 1994, Normal variation in the lateral ventricles of the canine brain. Vet Radiol Ultrasound. 35, 83-87.
Davidson H, Kraft SL, 1994, Imaging Diagnosis (MRI of a Canine Retrobulbar Lymphosarcoma). Vet Radiol Ultrasound. 35, 282-283.
Desrochers A, St.-Jean G, Kraft SL, Leipold HW, 1994, Type I Congenital cystic adenomatoid malformation of the lungs in a Hereford calf, J Vet Med A. 41, 709-712.
Gavin PR, DeHaan CE, Kraft SL, Swartz CD, Griebenow ML, 1994, Large animal tissue tolerance with boron neutron capture. Int J of Radiat Oncol. 28, 1099-1106.
Gavin PR, Huiskamp R, Wheeler FJ, Kraft SL, DeHaan CE, 1993, Large animal normal tissue tolerance using an epithermal neutron beam and borocaptate sodium. Strahlenther Onkol. 1, 48-56.
Yvorchuk K, DeBowes R, Kraft SL, 1993, Trichophytobezoar in a foal. Cornell Vet. 83, 169-175.
Kraft SL,
Gavin PR, Leathers CW, DeHaan CE, Bauer WB, Miller DL, Dorn RV, 1992,
Borocaptate sodium: A potential boron-carrying compound for Boron
Neutron Capture Therapy. Proc Natl Acad Sci USA. 89, 11973-11977.
Moore MP, Gavin PR, Kraft SL,
De Haan CE, Leathers CW, Dorn RV, 1991, MR, CT and clinical features
from dogs with nasal tumors involving the rostral cerebrum and nasal
passages. Vet Radiol. 32, 19-25.
De Haan CE, Papageorges M, Kraft SL, 1991, Radiographic diagnosis: solitary pulmonary nodule in a dog. Vet Radiol. 32, 75-77.
Moore MP, Greene SA, Keegan RD, Gallagher LR, Gavin PR, Kraft SL,
De Haan CE, Klappenbach K, 1991, Quantitative electroencephalography in
dogs anesthetized with 2.0% end-tidal concentration of isoflurane
anesthesia. Am J Vet Res. 52, 551-560.
Stauber E, Murnane B, Kraft SL, Basaraba R, 1991, Case report: Multiple tumors in a ferret. J Small Exot Anim Med. 1, 87-89.
Kraft SL,
Gavin PR, Leathers CW, Wendling LR, Frenier SL, Dorn RV, 1990, Diffuse
cerebral and leptomeningeal astrocytoma in dogs: MR features, J Comput Assist Tomogr. 14, 555-560.
Frenier SL, Kraft SL, Moore MP, Gavin PR, 1990, A review of canine intracranial astrocytomas and comparison with the human counterpart. Compend Cont Educ. 12, 1422-1436.
Kraft SL, Gavin PR, Moore MP, Leathers CW, Richardson TE, 1990, Imaging Diagnosis, Canine Meningioma. Vet Radiol. 31, 65-67.
Gavin PR, Kraft SL, Wendling LR, Miller D, 1989, Canine Spontaneous Brain Tumors - A Large Animal Model for BNCT, Strahlenther Onkol. 165, 225-229.
Kraft SL, Gavin PR, Wendling LR, Reddy VK, 1989, Canine Brain Anatomy on Magnetic Resonance Images. Vet Radiol. 30, 147-158.
Kraft SL,
Evermann JF, Riggs M, McKeirnan AJ, 1985, Canine herpes virus infection
of the neonate and its role in mixed infections of older dogs. Compend Cont Educ. 8, 688-697.