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CSU Animal Cancer Center Clinical Trial

Patient Disease:
Soft Tissue Sarcomas

Study Name:
Post-operative Administration of Myxoma Virus to Reduce Recurrence of Soft Tissue Sarcomas in Dogs – A Pilot Study

Purpose of the study:

  • Oncolytic poxvirus therapy will reduce the rate of sarcoma recurrence
  • The goal is to evaluate the immune response to post-operative myxoma virus injection in dogs with soft tissue sarcomas

Primary Eligibility Criteria:

  • Biopsy-confirmed grade II or III soft tissue sarcoma that is not amenable to complete surgical resection
  • Dogs must be overall healthy with adequate blood work results

Study Protocol:

  • Pre-enrollment: Physical exam, labwork (blood tests, urinalysis), chest xrays, and biopsy if not already performed
  • Surgical excision of the tumor, with virus injection at the surgical site
  • Week 2: Recheck exam, labwork, and 2nd virus injection at surgery site
  • Rechecks at 4, 6, 8, and 12 weeks, and ongoing every 2 months for 12 months

Owner Responsibilities:

  • Costs of initial testing to determine eligibility (labwork, chest x-rays, and pre-treatment biopsy, as well as any other tests recommended by your pet's oncologist)

Financial Incentives:

  • Costs related to the surgery (anesthesia, histopathology, hospitalization, post-operative care, wound management), clinical trial appointments, physical examinations, recommended follow-up chest x-rays, blood work, urinalysis, and immunological studies will be covered by this study.

If you have further questions about any of our clinical trials, Please either login or sign up to submit a consulting form. Your consult will then be directed to an appropriate oncology clinician. Requests are typically returned within 5 business days